Dr. Tillerson-Brown is a professor of history, department chair, and dean of the Women's College at Mary Baldwin University in Staunton, Virginia. She also directs the African American Studies and Public History programs while advising Phi Alpha Theta, the national history honor society, and is a member of MBU’s Coalition for Racial & Social Justice. In addition, Tillerson-Brown is completing her book manuscript, Black Women and the Freedom Struggle in Prince Edward County, Virginia, 1880-1965.
In 2013, Dr. Tillerson-Brown produced a documentary, Voices from Port Republic Road. Focusing on the experiences of alumni from the Rosenwald School, this project documents the interconnectedness of school, church, and business in this mid-twentieth-century rural Black community along with the challenges of public school segregation and integration.
Before accepting her position at Mary Baldwin, she was director of African American Heritage Program at the Virginia Foundation for the Humanities at UVA. She worked as a public school teacher and counselor in Roanoke City Public Schools and Baltimore City Public Schools.